Welcome to Spidikor.com
This is a hub for all my neuropsychopharmacology research, which consists of notes on scientific papers, articles with my novel findings, and soon, editorials. Feel free to take a look around!
Check out SpidikorLM, the AI model trained on my notes! Ask it how NSI-189 works!
Greetings! I am Spidikor.
I am an independent autodidactic neuropsychopharmacology researcher who has been teaching myself this material for a decade. I am interested in this topic at every level of magnification: I analyze the molecular dynamics of ion channels and receptors, their downstream intracellular signaling pathways, the structure and regional differences in function of neuroanatomy, and the macro-scale psychological and behavioral changes that result from manipulating these pathways. My goal is to elucidate the mechanisms that link these distinct layers of emergence.
A perfect example of this is my "canon event" Reddit post, in which I brought to light the finding that the mechanism of action of the neurogenic compound NSI-189 (aka Amdiglurax) is not, in fact, “unknown,” as almost every source claims. It is an agonist of the nuclear receptor TLX (aka NR2E1), as confirmed by early patent literature. Agonism at this receptor activates neural stem cells to grow and proliferate. My discovery explained the functional neurogenic effects of NSI-189 by revealing its target; the master regulator of neural stem cells, TLX. My discovery was the result of extensive internet sleuthing and mechanistic cross-referencing. These notes on NSI-189 and TLX serve as a representative example of the copious amount of effort I put into the work showcased on this site. They stand out as a proud achievement of mine.
As previously mentioned, I operate completely independently and without funding. I am not affiliated with any organization or academic institution, and have received no formal education on this subject. Rather, my research is self-directed and self-taught over the course of 10y. I am fueled by passion and driven by my insatiable curiosity. I have a strong desire to collect and share the information I learn, help people using said knowledge, and make friends along the way. If you are curious about my research, have a question, or just want to chat, feel free to shoot me a DM on Discord! I accept almost all friend requests, given they aren’t bots, and I’m always willing to help people out with personalized suggestions and detailed explanations, free of charge! Yes, that means you!
A bit more about me:
I have ADHD, Autism, Bipolar I, and OCPD. My IQ is 134, but I am aware that IQ, as a measure, is far from the full picture of intelligence.
I am non-binary and use they/them pronouns. I have never felt any meaningful attachment to an internal gender, and have always felt exempt from the concept. I have been living authentically as myself for 8y now. Social and hormonal transition have vastly improved my life and have allowed a high level of self-acceptance as well. I am aware that many in the biohacking and nootropics communities are uncomfortable with the trans and enby communities. But let’s face it. We are all biohackers here. You are allowed to experiment with novel research compounds with largely unknown safety profiles, but I am not allowed to biohack my gender? Come on.
During my 8y living as myself, I’ve heard every variation of the same old uninspired insults and talking points paraphrased from alt-right podcasters. As stated previously, I am fully confident in who I am. If you are looking to “trigger the libs,” or to “debate” me in bad-faith about my own life experience, please know that I won’t bother engaging. My time is valuable and I will not waste it by arguing with people on the internet.